Safari Adventures: Africa [Wii]
- Developer:
- Type: Adventure
- Publisher: ElektroGames
- Released: 03 Nov 2009
Price: NA
Safecracker [Wii]
- Developer:
- Type: Puzzle
- Publisher: Daydream Software
- Released: 03 Dec 2008
Price: NA
Saint [Wii]
- Developer:
- Type: Shooter
- Publisher: Starfish
- Released: 21 Jul 2009
Price: NA
Sakura Wars: So Long, My Love [Wii]
- Developer:
- Type: Role-Playing
- Publisher: RED
- Released: 24 Mar 2010
Price: NA
Sam & Max: Season One [Wii]
- Developer:
- Type: Compilation
- Publisher: Telltale Games
- Released: 14 Oct 2008
Price: NA
Samba de Amigo [Wii]
- Developer:
- Type: Simulation
- Publisher: Gearbox Software
- Released: 23 Sep 2008
Price: NA
Samurai Shodown Anthology [Wii]
- Developer:
- Type: Compilation
- Publisher: Terminal Reality
- Released: 14 Apr 2009
Price: NA
Samurai Warriors: Katana [Wii]
- Developer:
- Type: Action
- Publisher: Omega Force
- Released: 15 Jan 2008
Price: NA
Scarface: The World is Yours [Wii]
- Developer:
- Type: Action
- Publisher: Radical Entertainment
- Released: 26 Jun 2007
Price: NA
Scene It? Bright Lights, Big Screen [Wii]
- Developer:
- Type: Traditional
- Publisher: Artificial Mind & Movement
- Released: 17 Nov 2009
Price: NA