Obscure: The Aftermath [Wii]
- Developer: Ignition Entertainment
- Type: Adventure
- Publisher: Hydravision Entertainment
- Released: 25 Mar 2008
Price: NA
Ocean Commander [Wii]
- Developer:
- Type: Shooter
- Publisher: Cyber Planet Interactive
- Released: 18 Nov 2008
Price: NA
Octomania [Wii]
- Developer:
- Type: Puzzle
- Publisher: Compile Heart
- Released: 25 Mar 2008
Price: NA
Offroad Extreme! Special Edition [Wii]
- Developer:
- Type: Racing
- Publisher: Data Design Interactive
- Released: 20 Nov 2007
Price: NA
Offshore Tycoon [Wii]
- Developer:
- Type: Simulation
- Publisher: Cyber Planet Interactive
- Released: 18 Nov 2008
Price: NA
Okami [Wii]
- Developer: Capcom
- Type: Action
- Publisher: Ready At Dawn Studios
- Released: 15 Apr 2008
Price: NA
One Piece: Unlimited Adventure [Wii]
- Developer: Namco Bandai Games America, Inc.
- Type: Action
- Publisher: Namco Bandai Games America, Inc.
- Released: 22 Jan 2008
Price: NA
Onechanbara: Bikini Zombie Slayers [Wii]
- Developer:
- Type: Action
- Publisher: Tamsoft
- Released: 10 Feb 2009
Price: NA
Open Season [Wii]
- Developer: Ubisoft Entertainment
- Type: Action
- Publisher: Ubisoft Montreal
- Released: 01 Dec 2006
Price: NA
Opoona [Wii]
- Developer: KOEI Corporation
- Type: Role-Playing
- Publisher: Omega Force
- Released: 25 Mar 2008
Price: NA